The ability to directly monitor head impact biomechanics using wearable sensors has fundamentally changed our understanding of the corresponding risks in a wide range of sports. One key finding is that significant tissue damage and changes in neural connectivity may result even in the absence of clinically diagnosed concussion symptoms. We will discuss our recent advances in evolving wearable sensors into advanced neuro-trauma dosimeters, suitable for monitoring cumulative damage due to repetitive head impacts and developing remove-from-play thresholds. These efforts combine measured head impact biomechanics, finite element modeling of the corresponding forces generated in the brain, and high resolution MRI imaging of the resulting changes in neural connectivity. We will also discuss related applications of wearable head impact sensors in the development of new concussion diagnostics such as blood biomarkers and eye tracking.